Recurrent upper respiratory tract infections (URTIs) are highly prevalent among school-aged children and significantly impact health, attendance, and quality of life. This prospective case series assesses the effectiveness of individualized homeopathic treatment in reducing the severity of URTIs using the Jackson Scoring System. Forty-five children aged 5–15 years with recurrent URTIs were evaluated using Jackson scores before treatment and after a 6-month follow-up period. Individualized homeopathic remedies were prescribed based on symptom totality. Comparative analysis demonstrated a meaningful reduction in Jackson scores posttreatment, indicating improvement in URTI severity. The study suggests that individualized homeopathic medicine may provide symptomatic relief and decrease infection burden in children with recurrent URTIs.