This research aimed to explore the impact of indicated Homoeopathic medicines and also Jaborandi mother tincture in the treatment of hyperhidrosis. Research conducted at OPD of Motiwala (national) Homoeoathic medical college and hospital of a six-month duration. The included age group of 18 to 40 years. Sample size of 30 patient divided into 2 group of control and experimental group. Experimental group received the Jaborandi mother tincture and control group received the individualised Homoeoathic medicines, their data were collected by case records format and perspiration score were measure by visual score. Pre and post score were measured. And by statistical analysis result were concluded. 100% patient showed improvement who received individualised Homoeoathic medicines .Aim and Objectives: This research aimed to explore the impact of indicated Homoeopathic medicines and also Jaborandi mother tincture in the treatment of hyperhidrosis and to compare their result. The primary objectives included to study the effect of Jaborandi Mother tincture in treating hyperhidrosis using visual scale for quantification of hyperhidrosis cases. And also to study the effect of individualised homeopathic medicine in cases of hyperhidrosis. Materials and Methods: This research adopts a Comparative study design conducted at OPD of Motiwala (national) Homoeoathic medical college and hospital of a six-month period. The selection of study subjects follows specific eligibility criteria, including an age group of 18 to 40 years, and obtaining written consent. Exclusion criteria encompass pregnant and lactating females , known cases of systemic diseases. Perspiration score measured by visual scale a sample size of 30 patient. Visual scale is employed for measurement and Data management involves the format of case record format. 30 sample size divide into control and experimental group. Experimental group received the Jaborandi mother tincture and Control group received the individualised Homoeoathic medicine. Statistical analysis is planned using unpaired t test and Microsoft excelPositive and negative assessments are made based on score improvements or lack thereof. Graphical presentation and statistical evaluation will contribute to the conclusion drawn from this comprehensive research .Results: According to statistical analysis the Calculated value of t is 3.125 and Table t value is 2.15. Hence calculated t value is greater than table t value. 73% patient showed improvement out of 15 Patient who received jaborandi mother tincture , and 100% patient improved who received individualised Homoeoathic medicines. Conclusion: Since calculated t value is greater than table t value null hypothesis is rejected thus jaborandi mother tincture is as effective as individualised homoeopathic medicine in treatment of hyperhidrosis in the age group of 18 to 40 years.