Bowel Nosodes has been invented since 1920 ,they are less used by Homoeopathic Practitioners due to limited studies,so this a small attempt to observe and study the efficacy of Bowel Nosode in Chronic diseases. Objective: 1.To identify the utility of Bowel Nosode in Treatment of Chronic Diseases. 2.To identify the commonly prescribed Bowel Nosode Methods: The Case series includes study includes 15 cases of chronic disease, of which all cases were administered the Bowel Nosode selected on the basis of totality of symptoms . Convenience Sampling was done. Results: Out of 15 cases 3 cases are improving, 3 cases are not improving and 9 cases are improved. Conclusion: Administration of Bowel Nosodes based on totality of symptoms is found to be useful.