Gastro- oesophageal reflux (GOR) is defined as backward flow of gastric contents into the oesophagus. A small amount of GOR occurs in normal individuals; the term GORD (gastro- oesophageal reflux disease) includes all the symptoms and forms of tissue damage secondary to the reflux of gastric contents into the oesophagus. Homoeopathic medicines are known for curative effect, by prevention of further complication by treating with homoeopathic medicines and doing necessary interventions Method- we carried out randomized control trial for the cases of Gastro Oesophageal Reflux disease for 30 cases. Natrum phos. along with homoeopathic medicine in experimental group and homoeopathic medicine control group. Conclusion- In qualitative study Natrum phos. is having good potential in cases of GORD but quantitative aspect of our study reflects Homoeopathic Medicine alone has good scope.