Leucorrhea is abhorrent condition, experienced by many women. This is a case report of patient suffering from Leucorrhea, treatedwith homoeopathic medicine. Followed by Homoeopathic case taking and based on the totality of symptoms sepia was prescribed in accordance with the principles of homoeopathy. The patient got relieved of the condition, which shows the efficacy of Sepia, Homeopathic medicine in treatment of Leucorrhoea.