Background: Anaemia in females of reproductive age are at high risk. Objective: The objective of this study is compare the effectiveness of Individualized Homoeopathic medicine along with Ferrum phos 6X and Lecithin 12C alone in treatment of anemia and secondary objective is to find out common causes of anemia. Materials and Methods: Comparative study was done for 6months and sample were taken from Motiwala Hospital OPD and Medical camps through Simple random Sampling technique 46 sample size were selected according to our inclusion criteria (females of 13 to 49 years of age, Hb ranging from 7 to 12gm/dl, patient who have given consent and who have fulfilled the criteria for questionnaire) and complete blood count was done. The sample were divided into two, Group A were given Individualized homoeopathic medicine along with Ferrum phos 6X and Ferrum phos 6X was repeated in every follow up. Group B was given Lecithin 12C and it was repeated in alternate follow up. After 6 follow ups again complete blood count was done and result were formed accordingly. Results: 135 patients were screened and out of which 46 sample size was selected, the calculated t value 2.20 significantly exceeds the table t value 2.02. Hence it was considered that the study is statistically significant. Among 46 cases of anemia, the most common cause was nutritional deficiency due to improper dietary intake (36 cases, 78.26%) followed by recurrent infection (5 cases, 10.87%), heavy menstrual bleeding (4 cases, 8.70%) and hemorrhoids (1 case, 2.17%).. Conclusion: Hence we concluded that both individualized homeopathic medicine with Ferrum phos 6X and Lecithin 12C are effective in treating anemia, but their impact is unequal. The combination of homeopathic medicine with Ferrum phos 6X showed significantly better improvement in anemia compared to Lecithin 12C.