Background: -Menopause is the point at which menstruation permanently stops due to loss of ovarian follicular functions (1), marking the end of woman’s reproductive cycle. This effects the women mentally and physically. Objective: - To study the reduction in severity of symptoms after prescribing individualized homoeopathic medicine in women with menopausal syndrome and To study the frequently used medicines effective in reducing the severity of symptoms in women with menopausal syndrome Methods: The study employed case series design included 45 cases selected through the simple random sampling (convenient) from the OPD of the college hospital, as well as from peripheral OPD. Results: The 41 patients i.e. 91% patients improved and while 4 patients i.e.9% patient did not show the marked improvement. Conclusion: Homoeopathic medicines are efficacious in management of the Menopausal syndrome in women above 45 years.