Dentistry has come a long way from past to present in providing dental care to patients. Now, our main focus is to preserve tooth as we have realized the importance of tooth in our life. Nowadays, many of the dental professionals are facing difficulties in managing acute or chronic toothache or other recurrent dental issues due to recurring symptoms. Sometimes, there may be other health related issues or co-morbidities that works continuously for maintaining the dental health of the individual on which Homoeopathy has great influence. Homeopathy is the system of medicine based on nature’s law of cure i.e. like cures like; that is recognized for safe and effective treatment. Homoeopathy in dentistry is a less visited system of medicine in the management of orofacial diseases. Homoeopathy is a safe and natural alternative that is effective in all ages. Homeopathic remedies are used in the field of dentistry to improve individual’s psychological or emotional condition with minimal or no side effects of conventional drugs. Homoeopathy can be safely used for the pain management that may be acute or chronic including acute dental emergencies. Homeopathy is not a replacement to dental care but can be safely used along with the conventional line of treatment(1).The present scientific literature based review is an attempt to highlight the possible role of Homeopathy in the management of various orofacial disorders.